Predictors of multi-organ dysfunction in heatstroke

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Predictors of multi-organ dysfunction in heatstroke.

BACKGROUND Heatstroke is a medical emergency that results from failure of thermoregulatory mechanism coupled with an exaggerated acute phase response, causing an elevation in core body temperature that rises above 40 degrees C, producing multi-organ dysfunction. It carries a high mortality rate, and in survivors, a risk of permanent neurological damage. OBJECTIVE To investigate predictors of ...

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Acute Multi Organ Dysfunction Syndrome

Severe sepsis and multiorgan dysfunction syndrome may develop in the course of severe sepsis, intoxication, poisoning, crush injury, asystole, drowning, and several other complications. When normal intensive care is insufficient despite vasoactive drugs, respiratory aid, and dialysis, the risk for death is extremely high. Only very little benefit has been noted in various trials using drug admi...

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Multiple organ dysfunction due to heatstroke after sauna: case report and review of the literature

Heatstroke usually occurs in summer during heat waves, and few cases occur in winter. We report the case of a 26-year-old man who went through multiple organ dysfunction after sauna in January, and finally was diagnosed as heatstroke.

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Melatonin Improves Outcomes of Heatstroke in Mice by Reducing Brain Inflammation and Oxidative Damage and Multiple Organ Dysfunction

We report here that when untreated mice underwent heat stress, they displayed thermoregulatory deficit (e.g., animals display hypothermia during room temperature exposure), brain (or hypothalamic) inflammation, ischemia, oxidative damage, hypothalamic-pituitary-adrenal axis impairment (e.g., decreased plasma levels of both adrenocorticotrophic hormone and corticosterone during heat stress), mul...

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Insulin Resistance as Prognostic Indicator in Multi Organ Dysfunction Syndrome

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ژورنال

عنوان ژورنال: Emergency Medicine Journal

سال: 2005

ISSN: 1472-0205,1472-0213

DOI: 10.1136/emj.2003.009365